2013年2月4日星期一

India looking at machine to detect drug-resistant TB

  The world's only diagnostic tool that can detect multi-drug resistant tuberculosis (MDR TB) in less than two hours time instead of the present method than can take upto two months, has passed the litmus test.The Xpert MTB test that is presently being analysed by India and is expected to be rolled out across the country soon, has been found to accurately and quickly detect TB.A review published on Friday, which assessed the diagnostic accuracy of the test was found to simultaneously detect TB and resistance to rifampicin, as an indicator of MDR.Like sputum smear microscopy, which relies on detecting TB with a microscope in a laboratory, Xpert requires a sample of sputum. However, while thousands of bacteria must be present in each millilitre of sample for TB to be detected under the microscope, Xpert can detect TB bacteria at much lower concentrations.In addition, the conventional microscopy approach does not detect drug resistance. Instead, TB has to be grown in the lab.This presents problems, especially for MDR TB, due both to the length of time required for the cultures to grow and the specialized laboratories and highly skilled staff needed.structural steelThe researchers, from the Cochrane Infectious Diseases Group (CIDG), McGill University and the Foundation for Innovative New Diagnostics (FIND), analysed data from 18 studies involving a total of 7816 people and found that when Xpert is used to screen 1,000 people, 150 of whom have TB,You will find it impossible to keep a sharp edge on it and using cheap all in one touch pos terminal can put more stress on your body and lead to developing carpal tunnel syndrome. it picks up 132 of the 150 cases (88%) and falsely diagnoses 17 (2%) with TB.metal machining "This study represents the most comprehensive review on the diagnostic accuracy of Xpert and may help countries make decisions about scaling up its use for management of TB and drug-resistant TB," said Karen Steingart of the CIDG.Service is increasingly important and the economically developed Earth auger areas will continue to maintain a large and active consumer demand for industrial aluminum profile in favor of the further.Karin Weyer from WHO said "Recent price reductions have greatly facilitated roll-out of this technology.If you cook a lot you will find that the work goes much faster and takes less effort with a quality Thermal printer OEM.Do not buy cheap cooking knives at your local big box retail outlet. Around 1.4 million test cartridges and over 200 GeneXpert instruments for the rapid detection of TB and rifampicin resistance will be distributed in 21 countries with a high burden of TB."In a major breakthrough recently, an agreement was reached which reduced the cost of Xpert by 40% - a a price that will not increase until 2022.The only method used in most laboratories in India till now is smear microscopy, a technique developed in the 1880s by the German bacteriologist Robert Koch that requires visual detection of the TB bacterium under a microscope. Smear microscopy is insensitive for diagnosing TB in patients who are co-infected with HIV and also does not detect MDR TB.

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